Perioperative medicine & outcomes
Ventilatory efficiency as a prognostic factor for postoperative complications in patients undergoing elective major surgery: a systematic review
Authors' conclusion
This systematic review identifies VE/VCO2 as a predictor for short-term complications after thoracic and abdominal surgery.
Study context
- Population
- Patients undergoing elective major surgery65 studies
- Outcome
- Ventilatory efficiency (VE/VCO2) as a prognostic factor for postoperative complications
Pooled result
As reported in the abstract
- VE/VCO2 reported as a prognostic factor for short-term complications after thoracic and abdominal surgery
- Adjusted associations extracted from 32 studies, unadjusted from 33 studies
Further pooled results
Mid- to long-term mortality
- VE/VCO2 reported as a prognostic factor for mid- to long-term mortality
Risk of bias and covariable selection
- Studies applying data-driven covariable selection
- 31
- Studies excluding VE/VCO2 from final multivariable regression owing to data-driven model building
- 18
- Risk of bias a concern in domains 'study confounding' and 'statistical analysis'
Original publication
Ventilatory efficiency as a prognostic factor for postoperative complications in patients undergoing elective major surgery: a systematic review. Br J Anaesth. Published 20 April 2024. doi:10.
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