Perioperative medicine & outcomes
Different measures of ventilatory efficiency in preoperative cardiopulmonary exercise testing are useful for predicting postoperative complications in abdominal cancer surgery
Authors' conclusion
Both preoperative VE/VCO2 slope and PetCO2 could identify subjects with a very high risk of complications following oesophageal resection, with similar prognostic utility.
Study context
- Population
- Patients undergoing preoperative cardiopulmonary exercise testing (CPET) before oesophageal and other major abdominal cancer surgery, 2008–2023
- Participants
- 116 patients
- Exposure
- VE/VCO2 slope vs PetCO2
- Outcome
- Major cardiopulmonary complication during hospitalisation or death
- Follow-up
- ≤90 days of surgery
Main finding
As reported in the abstract
Prediction of MCPC or death (oesophagus cancer)
| Group | AUC | 95% CI | Threshold | CI |
|---|---|---|---|---|
| VE/VCO2 slope | 0.70 | 0.51-0.89 | >38 | |
| PetCO2 | 0.71 | < 4.1 kPa (30.8 mmHg) | 0.53-0-90 |
AUC
VE/VCO2 slope0.70
PetCO20.71
95% CI
VE/VCO2 slope0.51-0.89
PetCO2— not stated in the abstract
Threshold
VE/VCO2 slope>38
PetCO2< 4.1 kPa (30.8 mmHg)
CI
VE/VCO2 slope— not stated in the abstract
PetCO20.53-0-90
Observational data: associations, not effects.
Further findings
Correlation between PetCO2 after 5-min warm-up and VE/VCO2 slope
- Strong negative correlation (Pearson r)
- −.88
Threshold analyses, other major abdominal surgery (subgroup)
- Threshold analyses non-significant
Original publication
Different measures of ventilatory efficiency in preoperative cardiopulmonary exercise testing are useful for predicting postoperative complications in abdominal cancer surgery. Acta Anaesthesiol Scand. Published 11 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →