Cardiac arrest & resuscitation

Visual coronary artery calcification score to predict significant coronary artery stenosis in patients presenting with cardiac arrest without ST-segment elevation myocardial infarction

Ann Intensive CarePublished Retrospective diagnostic accuracy study

Authors' conclusion

The present study found that a non-dedicated CT thorax may be useful to measure VCAC and if this is scored ≥ 4 it allows physicians to better select patients resuscitated from cardiac arrest with non-STEMI and without history of coronary artery disease who may benefit from an emergency coronary angiogram to detect a significant or culprit coronary artery stenosis and had PCI if appropriate.

Study context

Population
Patients with cardiac arrest without STEMI who had coronary angiogram and chest CT, Croix-Rousse Hospital, Lyon, France, January 2013 to March 2023
Participants
113 patients
Comparison
Visual coronary artery calcification (VCAC) score on chest CT to predict significant coronary stenosis, culprit lesion or percutaneous coronary intervention (PCI)
Outcome
Significant coronary artery stenosis on coronary angiogram
Methodological detailssingle-centre
  • Single-centre

Performance

As reported in the abstract

Significant coronary artery stenosis
Test or modelAUCOptimal thresholdSpecificitySensitivity
VCAC score0.95 (95%CI [0.90-1.00])≥ 494.7%91.9%

VCAC score

AUC0.95 (95%CI [0.90-1.00])
Optimal threshold≥ 4
Specificity94.7%
Sensitivity91.9%

Further findings

Culprit coronary artery stenosis (optimal threshold ≥ 5)

AUC
0.90 (95%CI [0.85-0.96])
Specificity
83.5%
Sensitivity
87.5%

Ad hoc PCI (optimal threshold VCAC ≥ 5)

AUC [0.823-0.948]
0.886
Specificity
81.8%
Sensitivity
85.7%

Delayed and ad hoc PCI (optimal threshold VCAC ≥ 5)

AUC [0.872-0.972]
0.921
Specificity
85.3%
Sensitivity
88.9%

Significant or culprit stenosis and ad hoc or delayed PCI (VCAC score ≥ 4)

Sensitivity
100%

Original publication

Visual coronary artery calcification score to predict significant coronary artery stenosis in patients presenting with cardiac arrest without ST-segment elevation myocardial infarction. Ann Intensive Care. Published 7 April 2025. doi:10.1186/s13613-025-01423-5

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