Cardiac arrest & resuscitation
In-Hospital cardiac arrest complicating ST-elevation myocardial Infarction: Temporal trends and outcomes based on management strategy
Authors' conclusion
Early PCI in STEMI impacts the natural history of IHCA including timing and type of IHCA.
Study context
- Population
- Adults with STEMI complicated by in-hospital cardiac arrest (IHCA), CABG excluded102,424 [2.6%] with IHCA
- Participants
- 3,967,711 adults
- Exposure
- Early percutaneous coronary intervention (PCI) vs delayed PCI vs medical management
- Outcome
- IHCA incidence
Methodological detailsNational Inpatient Sample (2000-2017)
- National Inpatient Sample (2000-2017)
Main finding
As reported in the abstract
Each group vs medical managementAdjusted odds ratio (95% CI)P value
Early PCI
0.44(0.43–0.44)
P < 0.001Delayed PCI
0.33(0.32–0.33)
P < 0.001Observational data: associations, not effects.
Further findings
| Outcome | Early PCI | Delayed PCI | Medical management | aOR (95% CI) | P value | |
|---|---|---|---|---|---|---|
| In-hospital mortalityEarly PCI vs Medical management | 49% | 50.9% | 82.5% | 0.18 (0.17–0.18) | P < 0.001 | |
| In-hospital mortalityDelayed PCI vs Medical management | 0.18 (0.17–0.19) | P < 0.001 | ||||
| 0.10.31310Adjusted odds ratio (log scale) |
Non-shockable rhythms
- Non-shockable rhythms: all p < 0.001
Safety
Multiorgan damage
Cardiogenic shock
- Multiorgan damage: all p < 0.001
- Cardiogenic shock: all p < 0.001
Original publication
In-Hospital cardiac arrest complicating ST-elevation myocardial Infarction: Temporal trends and outcomes based on management strategy. Resuscitation. Published 22 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →