Vitamin C and catheter-related bladder discomfort after transurethral resection of bladder tumor: A double-blind, randomized, placebo-controlled study
Primary resultResult — go to the resultRelative risk 0.426 95% CI 0.274–0.656Authors' conclusion
Patients who received vitamin C had decreased CRBD and improved patient satisfaction following transurethral resection of bladder tumor.
Study context
- Population
- Patients undergoing transurethral resection of bladder tumor, university tertiary hospital
- Participants
- 59 vs 59
- Comparison
- IV vitamin C 1 g vs normal saline after induction of anaesthesia
- Vitamin Cn = 59
- Controln = 59reference
- Primary endpoint
- Moderate or greater catheter-related bladder discomfort (CRBD)
- Follow-up
- Immediately postoperatively
Methodological detailsdouble-blind, placebo-controlled, single-centre
- Double-blind
- Placebo-controlled
- Single-centre
Primary result
As reported in the abstract
Relative risk
0.426
95% CI 0.274–0.656
P < 0.001
Events by treatment group
Vitamin C vs Control
RR 0.426 (95% CI 0.274–0.656); P < 0.001
Secondary outcomes
Moderate or greater CRBD · 1 h postoperatively
P = 0.003
Moderate or greater CRBD · 2 h postoperatively
P = 0.008
| Outcome | Vitamin C | Control | P value |
|---|---|---|---|
| Patient satisfaction scoreSignificantly higher with vitamin C | 5.0 ± 1.3 | 4.4 ± 1.4 | P = 0.009 |
Moderate or greater catheter-related bladder discomfort (CRBD) · 6 h postoperatively
- No significant difference
Original publication
Vitamin C and catheter-related bladder discomfort after transurethral resection of bladder tumor: A double-blind, randomized, placebo-controlled study. J Clin Anesth. Published 23 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →