ICU sedation, delirium & recovery

Wireless patches for continuous vital sign monitoring, symptoms and medication at the end-of-life in the palliative care unit: A prospective observational study

J Clin Monit ComputPublished Prospective observational study

Authors' conclusion

Continuous vital sign monitoring in palliative care using VitalPatches is feasible and depicts vital sign changes at the end-of-life. A positive correlation of HR with pain was detected.

Study context

Population
Adult terminal care patients in the palliative care unit at a tertiary-care hospital (05/2023–03/2024)90% with cancer
Participants
30 patients
Outcome
Feasibility of a wireless device (VitalPatches) for continuous vital sign monitoring (HR, respiratory rate, temperature) at the end-of-life
Methodological detailssingle tertiary-care hospital palliative care unit
  • Single tertiary-care hospital palliative care unit

Main finding

As reported in the abstract

HR change vs three days prior to death

Median patch duration (h, IQR 35-153)

88

HR increase at −2 days (bpm), p < 0.001

3.70

HR increase at −1 day (bpm), p < 0.001

7.64

HR increase on day of death (bpm), p < 0.001

12.26

Observational data: associations, not effects.

Further findings

Symptom load · until death

Symptom load increased until death, weakness and impaired vigilance prominent (p = 0.004)

Opioid use, patch start to end

Opioid use rose from 80 to 100% (p = 0.010)

Benzodiazepine use, patch start to end

Benzodiazepine use rose from 50 to 80% (p = 0.015)

Correlation of pain with HR

R (p < 0.001)
0.32

HR increase and imminent death

5 bpm HR increase over previous 24 h associated with death within following 24 h

Original publication

Wireless patches for continuous vital sign monitoring, symptoms and medication at the end-of-life in the palliative care unit: A prospective observational study. J Clin Monit Comput. Published 19 August 2025. doi:10.1007/s10877-025-01343-6

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