Neuroanesthesia & neurocritical care
Xenon and Argon as Neuroprotective Treatments for Perinatal Hypoxic-Ischemic Brain Injury: A Preclinical Systematic Review and Meta-Analysis
Study context
- Population
- Animal models of perinatal hypoxic-ischemic encephalopathy (HIE) (mice, rats, pigs)
- Participants
- 1,591 participants · 21 studies
- Comparison
- Xenon vs argon as neuroprotective treatments
- Outcome
- Neuroprotective efficacy
Methodological detailspairwise meta-analysis, random effects model, prospectively registered protocol
- Pairwise meta-analysis
- Random effects model
- Prospectively registered protocol
Pooled result
As reported in the abstract
Neuroprotective efficacy (summary estimate)
P < 0.001
- Both xenon and argon had significant neuroprotective efficacies
- P < 0.0001
Original publication
Xenon and Argon as Neuroprotective Treatments for Perinatal Hypoxic-Ischemic Brain Injury: A Preclinical Systematic Review and Meta-Analysis. Anesth Analg. Published 25 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →