Cardiac arrest & resuscitation
A quantitative evaluation of aerosol generation during cardiopulmonary resuscitation
Main finding · Peak aerosol concentration during ventilationResult — go to the resultFold difference 24Authors' conclusion
In conclusion, multiple components of cardiopulmonary resuscitation generate high concentrations of respiratory aerosol.
Study context
- Population
- Humans with OHCA undergoing CPR; porcine cardiac arrest model
- Participants
- 18 vs 16
- Comparison
- Cardiac arrest vs Control
- Cardiac arrestn = 18
- Controln = 16reference
- Outcome
- Exhaled respiratory aerosol concentration (optical particle sizer spectrometer)
Methodological detailsaerosol monitoring, human and porcine cardiac arrest model
- Aerosol monitoring
- Human and porcine cardiac arrest model
Main finding
Peak aerosol concentration during ventilation
Fold difference
24
P < 0.001
By group
As reported in the abstract
Further findings
Time-averaged aerosol concentration during ventilation, porcine model, vs before cardiac arrest
fold difference ≈270 · P = 0.008
Time-averaged aerosol concentration during ventilation, porcine model, vs before cardiac arrest
- Defibrillation and chest compressions generate high aerosol independent of, but synergistic with, ventilation
Original publication
A quantitative evaluation of aerosol generation during cardiopulmonary resuscitation. Anaesthesia. Published 3 November 2023. doi:10. 1111/ anae. 16162
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