A randomised controlled trial of the analgesia nociception index for intra‐operative remifentanil dose and pain after gynaecological laparotomy
Study context
- Population
- Women scheduled for gynaecological laparotomy159 analysed
- Participants
- 170 women
- Comparison
- Analgesia nociception index vs SBP
- Analgesia nociception indexn = 80
- SBPn = 79reference
- Primary endpoint
- Proportion of women with pain scores ≥ 5 (scale 0-10)
- Follow-up
- Within 40 min of admission to recovery
Primary result
As reported in the abstract
Pain scores ≥ 5 (scale 0-10) within 40 min of admission to recovery
Proportion with pain scores ≥ 5, Analgesia nociception index vs SBP
62/80 (78%) vs. 64/79 (81%)
Further findings
- Fentanyl dose in recovery — Mean (SD) fentanyl dose in recovery, Analgesia nociception index vs SBP
- 53.6 (26.9) μg vs. 54.8 (20.8) μg · P = 0.74
- Intra-operative remifentanil dose — Intra-operative remifentanil dose, Analgesia nociception index vs SBP
- 0.124 (0.050) μg.kg-1 .min-1 vs. 0.129 (0.044) μg.kg-1 .min-1 · P = 0.55
Original publication
A randomised controlled trial of the analgesia nociception index for intra‐operative remifentanil dose and pain after gynaecological laparotomy. Anaesthesia. Published 23 March 2023. doi:10.
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