A systematic methodological evaluation of sepsis guidelines: Protocol for quality assessment and consistency of recommendations
Study context
- Population
- Clinical practice guidelines for adult sepsis management published 2004–2025 by recognized medical or governmental organizations
- Primary endpoint
- Methodological quality of sepsis guidelines (AGREE II, six domains) and consistency of key clinical recommendations
Methodological detailsAGREE II appraisal, artificial intelligence (AI)-assisted data extraction evaluation, Trends in guideline quality over time to be evaluated, Search of PubMed, EMBASE, Cochrane Library and professional society websites, AI tools to be evaluated vs human-driven methods for data extraction
- AGREE II appraisal
- AI-assisted data extraction evaluation
- Trends in guideline quality over time to be evaluated
- Search of PubMed, EMBASE, Cochrane Library and professional society websites
- AI tools to be evaluated vs human-driven methods for data extraction
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
A systematic methodological evaluation of sepsis guidelines: Protocol for quality assessment and consistency of recommendations. Acta Anaesthesiol Scand. Published 13 May 2025. doi:10.
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