Hemodynamics, fluids & transfusion

A systematic review and meta-analysis of systematic and topical tranexamic acid administration in aesthetic plastic surgery

Perioper Med (Lond)Published Systematic review and meta-analysis of randomised trials

Authors' conclusion

Tranexamic acid reduced blood loss in aesthetic plastic surgery.

Study context

Population
Patients undergoing aesthetic plastic surgery
Participants
960 patients · 11 studies
Comparison
Topical or systematic TXA vs control
Outcome
Total blood loss
Methodological detailsPRISMA guidelines
  • PRISMA guidelines

Pooled result

As reported in the abstract

MD

- 18.05

95% CI - 22.01, - 14.09P < 0.00001

Systematic TXA

MD

- 74.93

95% CI - 88.79, - 61.07P < 0.00001

Topical TXA

Further pooled results

OutcomeP value
Drainage outputTopical TXA vs ControlP < 0.0006

Drainage output

Topical TXA reduced drainage output

Original publication

A systematic review and meta-analysis of systematic and topical tranexamic acid administration in aesthetic plastic surgery. Perioper Med (Lond). Published 3 June 2024. doi:10.1186/s13741-024-00406-7

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