Hemodynamics, fluids & transfusion
A systematic review and meta-analysis of systematic and topical tranexamic acid administration in aesthetic plastic surgery
Authors' conclusion
Tranexamic acid reduced blood loss in aesthetic plastic surgery.
Study context
- Population
- Patients undergoing aesthetic plastic surgery
- Participants
- 960 patients · 11 studies
- Comparison
- Topical or systematic TXA vs control
- Outcome
- Total blood loss
Methodological detailsPRISMA guidelines
- PRISMA guidelines
Pooled result
As reported in the abstract
MD
- 18.05
95% CI - 22.01, - 14.09P < 0.00001
Systematic TXA
MD
- 74.93
95% CI - 88.79, - 61.07P < 0.00001
Topical TXA
Further pooled results
| Outcome | P value |
|---|---|
| Drainage outputTopical TXA vs Control | P < 0.0006 |
Drainage output
- Topical TXA reduced drainage output
Original publication
A systematic review and meta-analysis of systematic and topical tranexamic acid administration in aesthetic plastic surgery. Perioper Med (Lond). Published 3 June 2024. doi:10. 1186/ s13741-024-00406-7
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