Perioperative medicine & outcomes

Accuracy of continuous glucose monitoring during noncardiac surgery: a prospective, blinded observational multicentre cohort study

Br J AnaesthPublished Prospective observational cohort study

Main finding · Overall bias, CGM vs blood glucose, 3 timepoints in first 24 hResult — go to the resultMean difference (bias) 0.38 mM 95% CI 0.23–0.53

Authors' conclusion

The accuracy of state-of-the-art continuous glucose monitoring is sufficient for perioperative use and could enhance perioperative surveillance of dysglycaemia.

Study context

Population
Patients aged >50 yr undergoing noncardiac surgery requiring at least 24 h of hospital stay340 paired readings
Participants
118 patients
Exposure
Continuous glucose monitoring vs blood glucose
Outcome
Overall mean difference (bias) before surgery, at end of surgery, and 24 h after surgery (Bland-Altman analysis)
Methodological detailsblinded, multicentre
  • Blinded
  • Multicentre

Main finding

As reported in the abstract

Overall bias, CGM vs blood glucose, 3 timepoints in first 24 h

Mean difference (bias)

0.38 mM

95% CI 0.23–0.53

CGM vs Blood glucose
mean difference (bias) 0.38 mM (95% CI 0.23–0.53)

Observational data: associations, not effects.

Secondary outcomes

Bias before start of surgery

Bias (n=116)
1.08 mM (95% CI: 0.87-1.29)

Bias at end of surgery

Bias (n=113)
0.15 mM (95% CI: −0.15 to 0.46)

Mean absolute relative difference

Range
12.0% to 18.3%

Surveillance error grid analyses

CGM values within acceptable risk ranges
>98%

Original publication

Accuracy of continuous glucose monitoring during noncardiac surgery: a prospective, blinded observational multicentre cohort study. Br J Anaesth. Published 24 July 2025. doi:10.1016/j.bja.2025.05.057

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