Paediatric anaesthesia & critical care
Acute Kidney Injury Following Pediatric Liver Transplantation: A Single‐Center Retrospective Cohort Study
Authors' conclusion
The incidence of AKI following pediatric liver transplantation is high, with urine output criteria demonstrating substantial value in capturing evolving renal dysfunction, complementing the immediate risk stratification provided by serum creatinine.
Study context
- Population
- Pediatric liver transplant recipients, Beijing Friendship Hospital, 2016–2021
- Participants
- 336 recipients
- Outcome
- AKI incidence (KDIGO criteria)
- Follow-up
- 7 days post-transplant
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
AKI incidence · within 7 days post-transplant
Acute kidney injury (AKI) incidence
56.0%
188/336
Observational data: associations, not effects.
Further findings
Independent predictors of AKI (multivariate logistic regression)
| OR (95% CI) | P value | ||
|---|---|---|---|
| PELD score | 1.02 (1.01–1.04) | P = 0.009 | |
| Total intraoperative fluid volume | 1.01 (1.01–1.01) | P = 0.033 | |
| 0.512Odds ratio (log scale) |
AKI by creatinine vs urine output criteria
- Creatinine criteria cases
- 85 (25.3%)
- Urine output criteria cases
- 154 (45.8%)
- Agreement poor (weighted κ)
- 0.160
- Creatinine criteria captured immediate postoperative renal stress; urine output criteria identified evolving renal dysfunction
ICU LOS by AKI stage
- Stage 1 AKI prolonged ICU stay by
- 31.2% (p = 0.0054)
- Stage 2 AKI prolonged ICU stay by
- 47.0% (p = 0.0007)
Mortality
- Overall 28-day mortality
- 0.60%
- 3-year mortality
- 4.17%
- No significant differences across AKI stages
- P = 0.285
Original publication
Acute Kidney Injury Following Pediatric Liver Transplantation: A Single‐Center Retrospective Cohort Study. Paediatr Anaesth. Published 28 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →