Acute kidney injury in patients before and after extracorporeal membrane oxygenation (ECMO) – Retrospective longitudinal analysis of the hospital outcomes

Guru, PK; Balasubramanian, P; Ghimire, M; Bohman, JKK; Seelhammer, TG; Kashani, KB; Schears, GJ

doi:10.1016/j.jcrc.2024.154528

Organ support & nutrition

Acute kidney injury in patients before and after extracorporeal membrane oxygenation (ECMO) – Retrospective longitudinal analysis of the hospital outcomes

J Crit CarePublished 31 Jan 2024Retrospective longitudinal observational study

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Authors' conclusion

AKI before ECMO initiation and the need for RRT post-ECMO are independently associated with poor patient survival.

Study context

Population: Adults placed on ECMO, January 2000 to December 2015
Participants: 329 adults

Exposure: Acute Kidney Injury (AKI) before vs after ECMO initiation
Pre-ECMO AKIn = 176
Post-ECMO AKIn = 137reference
Outcome: Post-ECMO AKI and in-hospital mortality

Methodological detailssingle-centre

Single-centre

Main finding

As reported in the abstract

In-hospital mortality

Pre-ECMO AKI73%128 of 176

Post-ECMO AKI42%32

Observational data: associations, not effects.

Original publication

Acute kidney injury in patients before and after extracorporeal membrane oxygenation (ECMO) – Retrospective longitudinal analysis of the hospital outcomes. J Crit Care. Published 31 January 2024. doi:10.1016/j.jcrc.2024.154528

Read the original article ↗

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