ICU sedation, delirium & recovery

Age Moderates the Effect of Obesity on Mortality Risk in Critically Ill Patients With COVID-19: A Nationwide Observational Cohort Study*

Crit Care MedPublished Observational cohort study

Main finding · Hospital mortality by age subgroupResult — go to the resultAdjusted odds ratio 0.59 95% CI 0.36–0.96

Authors' conclusion

A higher BMI may be favorably associated with a lower mortality among those less than 45 years old.

Study context

Population
Critically ill patients with COVID-19 in the National Intensive Care Evaluation registry1,402 aged <45 yr
Participants
15,701 patients
Exposure
Body mass index (BMI) ≥30 kg/m² vs lower BMI, by age
Outcome
Hospital mortality
Methodological detailsnationwide registry analysis
  • Nationwide registry analysis

Main finding

Hospital mortality by age subgroup

Adjusted odds ratio

0.59

95% CI 0.36–0.96

P = 0.03

BMI ≥30 kg/m² vs BMI <30 kg/m²
aOR 0.59 (95% CI 0.36–0.96); P = 0.03

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeaOR (95% CI)P value
Hospital mortality, total sampleBMI ≥30 kg/m² vs BMI <30 kg/m²0.98 (0.90–1.06)P = 0.62

Original publication

Age Moderates the Effect of Obesity on Mortality Risk in Critically Ill Patients With COVID-19: A Nationwide Observational Cohort Study*. Crit Care Med. Published 10 February 2023. doi:10.1097/ccm.0000000000005788

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