ICU sedation, delirium & recovery
The effect of body mass index on short-term outcomes in nonagenarians and centenarians with critical illness: A retrospective cohort study
Authors' conclusion
In nonagenarians and centenarians admitted to the ICU, higher BMI was linked to lower in-hospital mortality, suggesting a protective effect.
Study context
- Population
- Nonagenarians and centenarians admitted to the intensive care unit (ICU) over a 15-year period
- Participants
- 12,510 participants
- Exposure
- Underweight, overweight and obese vs normal weight
- Normal weightn = 5,471reference
- Underweightn = 1,526
- Overweightn = 3,914
- Obesen = 1,599
- Outcome
- In-hospital mortality
Methodological detailsbi-national, entropy-weighted
- Bi-national
- Entropy-weighted
Main finding
As reported in the abstract
Each group vs normal weightRelative risk (95% CI)P value
Underweight
1.18(1.02–1.36)
P = 0.030Overweight
0.97(0.87–1.08)
P = 0.580Obese
0.76(0.64–0.90)
P = 0.001- Increasing body mass index (BMI) negatively associated with mortality
- P < 0.001
Observational data: associations, not effects.
Further findings
Cohort BMI
- Median BMI 24.4 kg/m²
- IQR 21.8-27.5
Requirement for inotropes, invasive ventilation or RRT
- BMI not associated with these requirements
Original publication
The effect of body mass index on short-term outcomes in nonagenarians and centenarians with critical illness: A retrospective cohort study. Anaesth Crit Care Pain Med. Published 29 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →