Pediatric anesthesia & critical care
Alveolar Dead Space Fraction Predicts Prolonged Central Venous Pressure Elevation Following Perioperative Extubation in Patients After Fontan Surgery
Authors' conclusion
AVDSF was associated with prolonged elevation of CVP after extubation following Fontan surgery.
Study context
- Population
- Patients <10 years undergoing Fontan surgery at Hokkaido University Hospital, 2013–2023
- Participants
- 94 patients
- Exposure
- Alveolar dead space fraction (AVDSF) vs Pulmonary vascular resistance
- Outcome
- Prediction of unfavorable response
Methodological detailssingle tertiary-care centre
- Single tertiary-care centre
Main finding
As reported in the abstract
| Strategy | AUC | Sensitivity | Specificity |
|---|---|---|---|
| AVDSF >0.12 | 0.845 | 76.5% | 92.2% |
| PVR >1.55 Wood units | 0.694 | 70.6% | 68.7% |
AUC
AVDSF >0.120.845
PVR >1.55 Wood units0.694
Sensitivity
AVDSF >0.1276.5%
PVR >1.55 Wood units70.6%
Specificity
AVDSF >0.1292.2%
PVR >1.55 Wood units68.7%
- Unfavorable responses
- 17 (18%)
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Alveolar Dead Space Fraction Predicts Prolonged Central Venous Pressure Elevation Following Perioperative Extubation in Patients After Fontan Surgery. J Cardiothorac Vasc Anesth. Published 16 May 2026. doi:10. 1053/ j. jvca. 2026. 05. 039
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