Pediatric anesthesia & critical care

Alveolar Dead Space Fraction Predicts Prolonged Central Venous Pressure Elevation Following Perioperative Extubation in Patients After Fontan Surgery

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Authors' conclusion

AVDSF was associated with prolonged elevation of CVP after extubation following Fontan surgery.

Study context

Population
Patients <10 years undergoing Fontan surgery at Hokkaido University Hospital, 2013–2023
Participants
94 patients
Exposure
Alveolar dead space fraction (AVDSF) vs Pulmonary vascular resistance
Outcome
Prediction of unfavorable response
Methodological detailssingle tertiary-care centre
  • Single tertiary-care centre

Main finding

As reported in the abstract

StrategyAUCSensitivitySpecificity
AVDSF >0.120.84576.5%92.2%
PVR >1.55 Wood units0.69470.6%68.7%

AUC

AVDSF >0.120.845
PVR >1.55 Wood units0.694

Sensitivity

AVDSF >0.1276.5%
PVR >1.55 Wood units70.6%

Specificity

AVDSF >0.1292.2%
PVR >1.55 Wood units68.7%
Unfavorable responses
17 (18%)

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Alveolar Dead Space Fraction Predicts Prolonged Central Venous Pressure Elevation Following Perioperative Extubation in Patients After Fontan Surgery. J Cardiothorac Vasc Anesth. Published 16 May 2026. doi:10.1053/j.jvca.2026.05.039

Composed by AI from the published abstract and checked against it. How Briefs are made →

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