Hemodynamics, fluids & transfusion
An increase in skin blood flow after red blood cell transfusion is associated with an improvement in organ function in critically ill patients
Primary result · SOFA response (≥ 1 point reduction)Result — go to the resultOdds ratio 2.64 95 % CI 1.25–5.41Authors' conclusion
An increase in SBFBT after RBCT was independently associated with a reduction of 1 point in SOFA score within 24 h after RBCT.
Study context
- Population
- Adult non-bleeding intensive care unit (ICU) patients receiving RBC transfusion
- Participants
- 175 patients
- Comparison
- Skin blood flow (SBF) responders vs SBF non-responders after RBC transfusion
- SBF respondersn = 77
- Primary endpoint
- Association between SBF responder status and SOFA responder status (≥ 1 point SOFA reduction within 24 h post-RBCT)
- Follow-up
- 24 h post-RBCT
Primary result
SOFA response (≥ 1 point reduction)
Odds ratio
2.64
95 % CI 1.25–5.41
P = 0.01
SBF responders vs SBF non-responders
OR 2.64 (95 % CI 1.25–5.41); P = 0.01
As reported in the abstract
- Sequential Organ Failure Assessment (SOFA) improved
- 103 (58.9 %)
Original publication
An increase in skin blood flow after red blood cell transfusion is associated with an improvement in organ function in critically ill patients. J Crit Care. Published 22 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →