Neuroanaesthesia & neurocritical care
Anaesthesia-related complications after endovascular therapy for acute ischaemic stroke under general anaesthesia with early extubation: A single-centre retrospective cohort study
Authors' conclusion
Complications occurred in 133 (18%) patients and were more frequent in those with higher NIHSS scores and posterior circulation occlusions. Patients with a complicated course had poorer functional outcomes at 3 months.
Study context
- Population
- Patients undergoing endovascular therapy (EVT) for acute ischaemic stroke under a standardised general anaesthesia (GA) protocol over a 4-yr period
- Participants
- 734 patients
- Exposure
- Complicated course vs Uncomplicated course
- Complicated coursen = 133
- Outcome
- Incidence of anaesthesia-related complications
- Follow-up
- 24 h post-EVT
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Anaesthesia-related complication (complicated course)
Complicated course
18%
133
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Mean difference (95% CI) | |
|---|---|---|
| Change in 24-h NIHSSSmaller improvement with complicated course | 5.4 (4.1–6.7) | |
| −50510Difference (linear scale) |
| Outcome | OR (95% CI) | |
|---|---|---|
| Pneumonia | 2.72 (1.66–4.48) | |
| Poor functional outcome (mRS 3-6) · 3 months | 3.65 (2.15–6.20) | |
| Mortality · 3 months | 4.20 (2.45–7.21) | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Anaesthesia-related complications after endovascular therapy for acute ischaemic stroke under general anaesthesia with early extubation: A single-centre retrospective cohort study. BJA Open. Published 10 April 2026. doi:10.
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