Neuroanesthesia & neurocritical care

Association of oxygenation levels after successful mechanical thrombectomy under general anesthesia and 3-month functional outcome in patients with acute ischemic stroke: A prospective observational study

Anaesth Crit Care Pain MedPublished Prospective observational study

Authors' conclusion

No association was found between 3-mo functional outcomes and post-procedure oxygenation levels in patients with AIS treated successfully with EVT under general anesthesia.

Study context

Population
Mechanically ventilated patients with acute ischemic stroke (AIS) (proximal anterior circulation occlusion) after successful endovascular treatment (EVT) under GA, admitted to ICU for delayed extubationmet inclusion criteria
Participants
210 participants
Exposure
PaO2 <150 mmHg vs PaO2 ≥150 mmHg within the first hour of ICU admission
  • PaO2 <150 mmHgn = 100reference
  • PaO2 ≥150 mmHgn = 108
Outcome
Favorable functional outcome (mRS ≤ 2)
Follow-up
3 mo

Main finding

As reported in the abstract

P = 0.579

Observational data: associations, not effects.

Further findings

Demographics, clinical factors, neurological status

No significant differences between the groups

Original publication

Association of oxygenation levels after successful mechanical thrombectomy under general anesthesia and 3-month functional outcome in patients with acute ischemic stroke: A prospective observational study. Anaesth Crit Care Pain Med. Published 21 February 2025. doi:10.1016/j.accpm.2025.101494

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