Neuroanesthesia & neurocritical care

Machine Learning analysis of functional outcome and hemodynamic parameters during stroke thrombectomy under general anesthesia

Anaesth Crit Care Pain MedPublished Post hoc analysis of a prospective cohort study

Authors' conclusion

These findings highlight distinct intraoperative hemodynamic patterns associated with outcomes after thrombectomy under general anesthesia

Study context

Population
Consecutive patients with anterior circulation acute ischemic stroke (AIS) undergoing mechanical thrombectomy under GA at a tertiary stroke center, March 2014–June 2019
Participants
229 patients
Primary endpoint
Functional independence (mRS score 0-2)
Follow-up
Three months
Methodological detailsmachine learning (XGBoost, SHAP), single tertiary stroke centre, consecutive patients, internal validation
  • Machine learning (XGBoost, SHAP)
  • Single tertiary stroke centre
  • Consecutive patients
  • Internal validation

Primary result

As reported in the abstract

Functional independence (mRS ≤2)

Achieved mRS score ≤2

101

44.1%

Model predictive performance (AUC ROC)

0.85

Original publication

Machine Learning analysis of functional outcome and hemodynamic parameters during stroke thrombectomy under general anesthesia. Anaesth Crit Care Pain Med. Published 7 November 2025. doi:10.1016/j.accpm.2025.101665

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