Obstetric anesthesia

Anaesthetic management of oncological disease in pregnancy: a narrative review

AnaesthesiaPublished Narrative review

Authors' conclusion

Effective and safe anaesthetic management of cancer in pregnancy requires a multidisciplinary approach to balance maternal and fetal safety, with a focus on careful planning and individualised care.

Study context

Population
Pregnant patients with cancer
Methodological detailsLiterature search of PubMed and Google Scholar, English peer-reviewed articles, 1 January 1990 to 30 July 2024
  • Literature search of PubMed and Google Scholar, English peer-reviewed articles, 1 January 1990 to 30 July 2024

Main finding

As reported in the abstract

  • Pregnancy does not appear to worsen cancer prognosis; diagnosis and treatment complicated by overlap of cancer symptoms with physiological changes of pregnancy and safety concerns
  • Ultrasound and MRI preferred imaging; careful use of ionising radiation advised
  • Surgery, chemotherapy and radiotherapy possible during pregnancy, with specific timing and modality considerations
  • Anaemia, poor nutrition and preterm birth are significant concerns
  • Operative births: neuraxial techniques preferred; GA may be required in complex cases
  • Oncological surgery preferably in second trimester, with consideration of fetal monitoring and steroids; RA if possible, uteroplacental perfusion maintained
  • Increased thromboembolism risk to be addressed postoperatively, with psychological support; multidisciplinary support incl. psychosocial care essential

Original publication

Anaesthetic management of oncological disease in pregnancy: a narrative review. Anaesthesia. Published 8 January 2025. doi:10.1111/anae.16489

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