Cardiothoracic & vascular anaesthesia

Analgesia for minimally invasive thoracic surgery: comparing thoracic paravertebral to erector spinae plane block—a retrospective single-center study

Reg Anesth Pain MedPublished Retrospective cohort study

Main finding · PACU opioid consumption (OME)Result — go to the resultDifference 9.4 mg less OME 95% CI −15.7 to −3.0

Authors' conclusion

TPVB compared with ESPB for MITS was associated with decreased opioid use in PACU and shorter PACU and hospital LOS.

Study context

Population
Patients undergoing one-sided Minimally Invasive Thoracic Surgery (MITS) with Thoracic Paravertebral Block (TPVB) or Erector Spinae Plane Block (ESPB), Beth Israel Deaconess Medical Center, 2020–2024
Participants
404 patients
Exposure
TPVB vs ESPB
  • TPVBn = 121
  • ESPBn = 283reference
Outcome
Opioid consumption in PACU (cumulative oral morphine equivalents, OME)
Methodological detailssingle-center, hospital registry data, multivariable negative binomial regression
  • Single-center
  • Hospital registry data
  • Multivariable negative binomial regression

Main finding

PACU opioid consumption (OME)

Difference

9.4 mg less OME

95% CI −15.7 to −3.0

P < 0.01

As reported in the abstract

Overall median (IQR) postanesthesia care unit (PACU) oral morphine equivalents (OME)
25.5 mg (15.0-42.5)

Observational data: associations, not effects.

Secondary outcomes

OutcomeDifference (min shorter) (95% CI)P value
Time to first opioid administrationPredicted11.4 (1.3–21.5)P = 0.03
OutcomeEstimateP value
PACU LOSAdjusteddifference 118 min shorter (95% CI −216 to −20)P = 0.02
Hospital LOSAdjusteddifference 1.2 fewer days (95% CI −1.6 to −0.7)P < 0.001

Original publication

Analgesia for minimally invasive thoracic surgery: comparing thoracic paravertebral to erector spinae plane block—a retrospective single-center study. Reg Anesth Pain Med. Published 30 September 2026. doi:10.1136/rapm-2026-108183

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