Perioperative medicine & outcomes

Analgesic benefits of single-shot versus continuous adductor canal block for total knee arthroplasty: a systemic review and meta-analysis of randomized trials

Reg Anesth Pain MedPublished Systematic review and meta-analysis of randomised trials

Authors' conclusion

Our results suggest that continuous catheter-based ACB does not enhance or prolong the analgesic benefits when compared with single-shot ACB for TKA over the first 48 hours postoperatively.

Study context

Population
Adults undergoing total knee arthroplasty (TKA)
Participants
1,185 adults · 11 RCTs
Comparison
Single-shot vs continuous adductor canal block (ACB)
Outcome
(1) AUC pain severity at rest and (2) cumulative opioid (oral morphine equivalent) consumption
Follow-up
First 48 hours postoperatively
Methodological detailsrandom effects (Hartung-Knapp-Sidik-Jonkman)
  • Random effects (Hartung-Knapp-Sidik-Jonkman)

Pooled result

As reported in the abstract

up to 48 hours postoperatively
  • No differences in rest pain severity (AUC) or cumulative opioid consumption

Further pooled results

Rest pain scores (recovery room, 12 and 24 hours), cumulative opioid consumption at 24 hours, functional recovery

No differences observed

Safety

OutcomeOR (95% CI)P value
Block-related complicationsFewer with single-shot ACB0.24 (0.14–0.41)P = 0.002

Opioid-related side effects

No differences observed

Original publication

Analgesic benefits of single-shot versus continuous adductor canal block for total knee arthroplasty: a systemic review and meta-analysis of randomized trials. Reg Anesth Pain Med. Published 8 November 2022. doi:10.1136/rapm-2022-103756

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