Analgesic Effectiveness of Motor-sparing Nerve Blocks for Total Knee Arthroplasty: A Network Meta-analysis
Authors' conclusion
The results suggest that continuous ACB, but not single-injection ACB and/or single-injection block at the iPACK, provides statistically superior analgesia when added to LIA for total knee arthroplasty compared to LIA alone.
Study context
- Population
- Patients undergoing total knee arthroplasty
- Participants
- 2,317 patients · 27 studies
- Comparison
- Single-injection or continuous adductor canal block (ACB) with or without single-injection iPACK block added to local infiltration analgesia (LIA) vs LIA alone
- Outcome
- Area-under-the-curve pain scores over 24 to 48 h; postoperative function at >24 h
Methodological detailsfrequentist approach
- Frequentist approach
Pooled result
As reported in the abstract
AUC 24- to 48-h pain: continuous ACB + iPACK highest P-score probability of being most effective
89%
Postoperative function: continuous ACB without iPACK highest P-score probability of being most effective
87%
Original publication
Analgesic Effectiveness of Motor-sparing Nerve Blocks for Total Knee Arthroplasty: A Network Meta-analysis. Anesthesiology. Published 26 June 2023. doi:10. 1097/ aln. 0000000000004667
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