Analgesic effects of ultrasound-guided preoperative posterior Quadratus Lumborum block in laparoscopic hepatectomy: A prospective double-blinded randomized controlled trial
Primary resultResult — go to the resultMean difference −3.3 mg 95% CI −11.9 to 5.4Authors' conclusion
Preoperative bilateral posterior QLB did not reduce cumulative opioid consumption during the first 24 h after laparoscopic hepatectomy.
Study context
- Population
- Patients scheduled for laparoscopic hepatectomy for hepatocellular carcinoma, single tertiary care centre
- Participants
- 94 patients
- Comparison
- Bilateral posterior QL block with ropivacaine vs 0.9% saline
- Quadratus lumborum block (QLB)n = 46
- Controln = 46reference
- Primary endpoint
- Cumulative opioid consumption
- Follow-up
- Initial 24 h post-surgery
Methodological detailsprospective, double-blinded, single-centre
- Prospective
- Double-blinded
- Single-centre
Primary result
As reported in the abstract
Mean difference
−3.3 mg
95% CI −11.9 to 5.4
P = 0.457
By group
QLB vs Control
mean difference −3.3 mg (95% CI −11.9 to 5.4); P = 0.457
Secondary outcomes
| Outcome | QLB | Control | P value |
|---|---|---|---|
| Resting pain score · 1 h post-surgerySignificantly lower in the QLB group | 5 (interval 4–6.25) | 7 (interval 4.75–8) | P = 0.035 |
Resting or coughing pain scores at other time points; other secondary outcomes (intraoperative and recovery parameters)
- No significant intergroup differences
Original publication
Analgesic effects of ultrasound-guided preoperative posterior Quadratus Lumborum block in laparoscopic hepatectomy: A prospective double-blinded randomized controlled trial. J Clin Anesth. Published 7 June 2024. doi:10.
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