Posterior quadratus lumborum block versus epidural analgesia for postoperative pain management after open radical cystectomy: A randomized clinical trial
Authors' conclusion
Opioid consumption did not differ significantly between posterior QLB and an epidural infusion with ropivacaine for the first 2 postoperative days following RC.
Study context
- Population
- Adults aged 18–85 with bladder cancer scheduled for open radical cystectomyincluded in the analyses
- Participants
- 20 vs 19
- Comparison
- Posterior quadratus lumborum block (QLB) vs epidural analgesia
- QLBn = 20
- Epidural analgesian = 19reference
- Primary endpoint
- Cumulative rescue opioid (oxycodone PCA) consumption
- Follow-up
- POD 0-2
Primary result
As reported in the abstract
Cumulative rescue opioid consumption, POD 0 (9-12 h) · POD 0
| Group | Value | Doses |
|---|---|---|
| QLB | 14 (interval (unspecified) 7.6–33.3) mg | 8 (3.6-15.7) |
| Epidural analgesia | 6.1 (interval (unspecified) 2.0–16.1) mg | 4 (1.3-8.5) |
Value
QLB14 (interval (unspecified) 7.6–33.3) mg
Epidural analgesia6.1 (interval (unspecified) 2.0–16.1) mg
Doses
QLB8 (3.6-15.7)
Epidural analgesia4 (1.3-8.5)
- QLB vs Epidural analgesia: P = 0.089 — mg
- QLB vs Epidural analgesia: P = 0.057 — doses
Secondary outcomes
Cumulative rescue opioid consumption (oxycodone) · POD 1 · mg
P = 0.749
Doses QLB 12 (5.5-23.0) · Epidural analgesia 10 (8-20) · P > 0.9
| Outcome | P value |
|---|---|
| Cumulative rescue opioid consumption (oxycodone) · POD 2mg | P = 0.749 |
| Cumulative rescue opioid consumption (oxycodone) · POD 2Doses | P > 0.9 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Posterior quadratus lumborum block versus epidural analgesia for postoperative pain management after open radical cystectomy: A randomized clinical trial. Acta Anaesthesiol Scand. Published 3 January 2023. doi:10.
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