Pediatric anesthesia & critical care
Anesthetic Implications and Physiologic Response to Transcatheter Pulmonary Flow Restrictor Placement in Neonates: A Single-Center Cohort Study
Authors' conclusion
PFR deployment results in stable ventilatory physiology and predictable saturation and hemodynamic responses.
Study context
- Population
- Neonates and infants with complex congenital heart disease undergoing sequential bilateral transcatheter pulmonary flow restrictor (PFR) implantation under GA, tertiary congenital cardiac catheterization laboratory
- Participants
- 22 neonates
- Outcome
- Intraprocedural physiologic responses (predeployment, after PFR 1, after PFR 2)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
SpO2 reduced from 93% to 88%
Friedman Q = 7.878
p = 0.019
MAP increased stepwise from 42.5 to 54.5 mmHg
Friedman Q = 21.04, p = 2.7 × 10⁻⁵
Heart rate reduced from 152 to 144 bpm
Friedman Q = 9.33
p = 0.0094
Observational data: associations, not effects.
Safety
Conversion from volatile to intravenous anaesthesia due to hemodynamic compromise
- Required conversion to intravenous anesthesia due to hemodynamic compromise
- 4
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Anesthetic Implications and Physiologic Response to Transcatheter Pulmonary Flow Restrictor Placement in Neonates: A Single-Center Cohort Study. J Cardiothorac Vasc Anesth. Published 8 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →