Pediatric anesthesia & critical care
Intra-operative physiologic interventions associated with postoperative neurological complications in neonates and infants: A secondary analysis of the NECTARINE cohort
Authors' conclusion
There was no association between unexpected intra-operative instability of systemic homeostasis necessitating a corrective action and subsequent neurologic complications; however, these findings do not necessarily indicate the absence of any effect of physiological disturbances on neurologic outcomes.
Study context
- Population
- Neonates and infants receiving anaesthesia for operative and nonoperative procedures, 165 hospitals in 31 countries
- Participants
- 5,504 neonates · 165 hospitals · 31 countries
- Comparison
- Interventions for intra-operative physiologic instability vs none
- Primary endpoint
- Postoperative neurologic complication
- Follow-up
- Up to 30 days postoperatively
Methodological detailsmulticentre, multivariable logistic regression
- Multicentre
- Multivariable logistic regression
Primary result
As reported in the abstract
Postoperative neurologic complication (whole cohort)
140 of 5504
2.5%
Original publication
Intra-operative physiologic interventions associated with postoperative neurological complications in neonates and infants: A secondary analysis of the NECTARINE cohort. Eur J Anaesthesiol. Published 2 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →