Anesthetic Techniques and Cancer Outcomes: What Is the Current Evidence?
Authors' conclusion
With the sole exception of peritumoral lidocaine infiltration in breast cancer surgery, these RCTs have indicated a neutral effect of anesthetic technique on long-term oncologic outcomes.
Study context
- Population
- Patients undergoing cancer surgery
- Comparison
- Anesthetic techniques and perioperative interventions and their effect on cancer outcomes
- Outcome
- Long-term oncologic outcomes
Main finding
As reported in the abstract
- Preclinical studies suggest some biologic plausibility that cancer cell function could be influenced
- Available clinical evidence suggests a neutral effect
- Observational studies of cancer outcomes after curative surgery under various anesthetic techniques report conflicting results
- Completed randomized clinical trials (RCTs) indicate a neutral effect of anesthetic technique on long-term oncologic outcomes, except peritumoral lidocaine infiltration in breast cancer surgery
Original publication
Anesthetic Techniques and Cancer Outcomes: What Is the Current Evidence? Anesth Analg. Published 4 October 2024. doi:10. 1213/ ane. 0000000000007183
Composed by AI from the published abstract and checked against it. How Briefs are made →