Anesthetic drugs & techniques

Anesthetic Techniques and Cancer Outcomes: What Is the Current Evidence?

Anesth AnalgPublished Narrative review

Authors' conclusion

With the sole exception of peritumoral lidocaine infiltration in breast cancer surgery, these RCTs have indicated a neutral effect of anesthetic technique on long-term oncologic outcomes.

Study context

Population
Patients undergoing cancer surgery
Comparison
Anesthetic techniques and perioperative interventions and their effect on cancer outcomes
Outcome
Long-term oncologic outcomes

Main finding

As reported in the abstract

  • Preclinical studies suggest some biologic plausibility that cancer cell function could be influenced
  • Available clinical evidence suggests a neutral effect
  • Observational studies of cancer outcomes after curative surgery under various anesthetic techniques report conflicting results
  • Completed randomized clinical trials (RCTs) indicate a neutral effect of anesthetic technique on long-term oncologic outcomes, except peritumoral lidocaine infiltration in breast cancer surgery

Original publication

Anesthetic Techniques and Cancer Outcomes: What Is the Current Evidence? Anesth Analg. Published 4 October 2024. doi:10.1213/ane.0000000000007183

Composed by AI from the published abstract and checked against it. How Briefs are made →

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