Cardiothoracic & vascular anesthesia

APECx —Anaesthesia, Perfusion and Surgical Practices in Cardiac Surgery: Main Study Protocol of a Modular Multiphase Prospective International Multicentre Observational Study

Acta Anaesthesiol ScandPublished Study protocol of a prospective multicentre observational cohort study

Study context

Population
Adult cardiac surgery patients in cardiac surgery centres worldwide
Methodological detailsmodular, multiphase, international, pilot study planned, Planned start 2026; multiple phases over a 10-year period, Biannual data collection: all consecutive eligible cases during 2 pre-specified consecutive weeks within a 3-month window, Web-based electronic case report form; minimised dataset of routinely obtained data, Outcomes include intensive care unit (ICU) and hospital LOS and in-hospital mortality, maximum follow-up 30 days, Approved by the Medical Ethics Review Committee of Amsterdam UMC
  • Modular
  • Multiphase
  • International
  • Pilot study planned
  • Planned start 2026; multiple phases over a 10-year period
  • Biannual data collection: all consecutive eligible cases during 2 pre-specified consecutive weeks within a 3-month window
  • Web-based electronic case report form; minimised dataset of routinely obtained data
  • Outcomes include ICU and hospital LOS and in-hospital mortality, maximum follow-up 30 days
  • Approved by the Medical Ethics Review Committee of Amsterdam UMC

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

APECx —Anaesthesia, Perfusion and Surgical Practices in Cardiac Surgery: Main Study Protocol of a Modular Multiphase Prospective International Multicentre Observational Study. Acta Anaesthesiol Scand. Published 27 February 2026. doi:10.1111/aas.70214

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