Respiratory failure & ventilation

Artificial Intelligence Algorithm to Monitor Inspiratory Muscle Effort and Patient-Ventilator Dyssynchrony During Mechanical Ventilation

Crit Care MedPublished Diagnostic accuracy study

Authors' conclusion

AI presented good performance in detecting high and low Pmus , and allowed the automatic detection of specific types of dyssynchronies. This novel noninvasive method was comparable to intermittent techniques requiring occlusion maneuvers.

Study context

Population
Adults under pressure support ventilation in 2 ICUs, University of São Paulo, Brazil4,918 cycles analysed
Participants
48 participants
Comparison
Artificial intelligence (AI)-estimated Pmus vs esophageal manometry and occlusion-based techniques
Outcome
Agreement with Pmus,es
Methodological detailsprospective, 2 ICUs
  • Prospective
  • 2 ICUs

Performance

As reported in the abstract

Test or modelBias95% limits of agreement
Pmus,AI0.9−5.1, 6.9

Pmus,AI

Bias0.9
95% limits of agreement−5.1, 6.9
Pmus,es range
1.0 to 28.4 cm H 2 O

Further findings

OutcomePmus,AI
Detection of extreme values of Pmus,es and dynamic driving pressure
AUCgreater than 0.8
Detection of ineffective effort, autotriggering or reverse triggering vs experts' classification
Sensitivity86.5%
Specificity77.4%

Accuracy vs occlusion-based techniques (pressure muscle index, Pocc)

Pmus,AI accuracy comparable to occlusion-based techniques

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Artificial Intelligence Algorithm to Monitor Inspiratory Muscle Effort and Patient-Ventilator Dyssynchrony During Mechanical Ventilation. Crit Care Med. Published 21 May 2026. doi:10.1097/ccm.0000000000007145

Composed by AI from the published abstract and checked against it. How Briefs are made →

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