Neuroanesthesia & neurocritical care
Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units
Main finding · Correlation between BIS and clinical sedation scoreResult — go to the resultCorrelation coefficient 0.17 95% CI 0.08–0.26Authors' conclusion
This study supports previous work showing that BIS decreases with decreasing sedation score. However, the variation in BIS values increased with deeper levels of clinical sedation.
Study context
- Population
- Patients with severe TBI sedated in four UK ICUs
- Participants
- 26 patients
- Outcome
- Relationship between BIS value and clinical sedation score
Methodological detailsmulticentre, blinded BIS data collection, Sedation management at the discretion of the ICU clinical team
- Multicentre
- Blinded BIS data collection
- Sedation management at the discretion of the ICU clinical team
Main finding
As reported in the abstract
Correlation between BIS and clinical sedation score · 24-h period
Correlation coefficient
0.17
95% CI 0.08–0.26
- Mean BIS (IQR 29-44)
- 38
Observational data: associations, not effects.
Further findings
BIS vs ICP, vasopressor use, osmotherapy use, need for additional sedative
- No statistically significant relationship
Original publication
Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units. BJA Open. Published 28 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →