ICU sedation, delirium & recovery
Association between acute disease severity and one-year quality of life among post-hospitalisation COVID-19 patients: Coalition VII prospective cohort study
Main finding · EQ-5D-3L utility scoreResult — go to the resultAdjusted difference - 0.1 95% CI - 0.15 to - 0.06Authors' conclusion
COVID-19 patients who needed mechanical ventilation during hospitalisation have lower 1-year quality of life than COVID-19 patients who did not need mechanical ventilation during hospitalisation.
Study context
- Population
- Adult post-hospitalisation COVID-19 patients, 84 sites in Brazil, March 2020–March 20221,156 with primary outcome data
- Participants
- 1,508 patients
- Exposure
- Acute disease severity score 5 vs score 2
- Outcome
- Utility score of EQ-5D-3L
- Follow-up
- 1 year
Methodological detailsnested in 5 randomised clinical trials, multicentre
- Nested in 5 randomised clinical trials
- Multicentre
Main finding
EQ-5D-3L utility score
Adjusted difference
- 0.1
95% CI - 0.15 to - 0.06
By group
Severity score 5
0.7
Severity score 2
0.84
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Severity score 2 | Severity score 5 | Adjusted difference (95% CI) | |
|---|---|---|---|---|
| All-cause mortality · 1 yearSeverity score 5 vs Severity score 2 | 1.2% | 7.9% | 7.1% (2.5%–11.8%) | |
| Major cardiovascular events · 1 yearSeverity score 5 vs Severity score 2 | 2.3% | 5.6% | 2.6% (0.6%–4.6%) | |
| New disabilities in instrumental activities of daily living · 1 yearSeverity score 5 vs Severity score 2 | 23.5% | 40.4% | 15.5% (8.5%–22.5) | |
| −100102030Difference (linear scale) |
Original publication
Association between acute disease severity and one-year quality of life among post-hospitalisation COVID-19 patients: Coalition VII prospective cohort study. Intensive Care Med. Published 3 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →