Perioperative medicine & outcomes
Association between Adherence to Patient Blood Management Recommendations and Postoperative Complications in Hip and Knee Arthroplasty
Main finding · 30-day postoperative complicationsResult — go to the resultAdjusted odds ratio 0.43 95% CI 0.32–0.58Authors' conclusion
Adherence to the PBM clinical pathway was associated with improved outcomes.
Study context
- Population
- Patients undergoing primary total knee or hip arthroplasty at 43 hospitals, 2016–2022
- Participants
- 30,926 patients · 43 hospitals
- Exposure
- Higher vs lower adherence to the patient blood management (PBM) clinical pathway
- Outcome
- Postoperative complications
- Follow-up
- 30 days
Methodological detailsmulticentre, multilevel multivariable regression
- Multicentre
- Multilevel multivariable regression
Main finding
30-day postoperative complications
Adjusted odds ratio
0.43
95% CI 0.32–0.58
P < 0.001
Higher PBM adherence
aOR 0.43 (95% CI 0.32–0.58); P < 0.001
As reported in the abstract
- Patients with 30-day postoperative complications
- 1,335 (4.3%)
- Median adherence to the PBM clinical pathway
- 60.0%
- Lower odds of MACE with higher adherence
- 65%
- Lower odds of infection with higher adherence
- 45%
Observational data: associations, not effects.
Secondary outcomes
Hospital LOS
| Adjusted incidence rate ratio (95% CI) | P value | ||
|---|---|---|---|
| Higher adherenceShorter hospital stays · sensitivity analyses confirmed these associations | 0.77 (0.76–0.79) | P < 0.001 | |
| 0.512Adjusted incidence rate ratio (log scale) |
Transfusion rate
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Higher adherenceReduced transfusion rates · sensitivity analyses confirmed these associations | 0.11 (0.09–0.14) | P < 0.001 | |
| 0.050.21520Adjusted odds ratio (log scale) |
Original publication
Association between Adherence to Patient Blood Management Recommendations and Postoperative Complications in Hip and Knee Arthroplasty. Anesthesiology. Published 14 March 2025. doi:10.
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