Perioperative medicine & outcomes
Association between Complications and Death Within 30 days after General Surgery: A Vascular Event in Noncardiac Surgery Patients Cohort Evaluation (VISION) Substudy
Authors' conclusion
The complications most associated with 30-day mortality following general surgery are major bleeding, sepsis, and MINS.
Study context
- Population
- Adult general surgery patients from the VISION cohort of non-cardiac surgery, followed for 30 daysgeneral surgery subset
- Participants
- 7,950 patients
- Exposure
- Patients with vs without each postoperative complication
- Major bleedingn = 1,454
- Sepsisn = 783
- MINSn = 980
- Outcome
- Mortality
- Follow-up
- 30 days
Methodological detailsmulticentre, 28 centers in 14 countries, adjusted Cox proportional hazards model
- Multicentre
- 28 centers in 14 countries
- Adjusted Cox proportional hazards model
Main finding
As reported in the abstract
30-day mortality
Adjusted hazard ratio (95% CI)P value
Major bleeding
2.49(1.87–3.33)
P < 0.001Sepsis
6.52(4.72–9.01)
P < 0.001MINS
2.00(1.50–2.67)
P < 0.001- Deaths within 30 days
- 240 (3.0%)
Observational data: associations, not effects.
Original publication
Association between Complications and Death Within 30 days after General Surgery: A Vascular Event in Noncardiac Surgery Patients Cohort Evaluation (VISION) Substudy. Ann Surg. Published 11 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →