Cardiothoracic & vascular anesthesia
Association Between COVID-19 Infection and Postoperative Outcomes Following Coronary Artery Bypass Grafting: A Retrospective Cohort Study
Authors' conclusion
COVID-19 infection within 2 weeks before CABG is associated with a significantly increased risk of complications.
Study context
- Population
- Adults undergoing coronary artery bypass grafting (CABG) during the COVID-19 pandemic, diverse US healthcare settings
- Exposure
- Preoperative COVID-19 infection vs no history of COVID-19
- Outcome
- Postoperative complications (ICD codes): Venous thromboembolism (VTE), sepsis, AKI, surgical site infection, acute myocardial infarction (AMI), 30-day mortality and 1-year mortality
Methodological detailsmulti-institutional, N3C database
- Multi-institutional
- N3C database
Main finding
As reported in the abstract
Postoperative complications, COVID-19 0 to 2 weeks before surgery
0 to 2 weeks vs COVID-19-negativeOdds ratio (95% CI)P value
VTE
2.29(1.36–3.59)
P = 0.001Sepsis
1.74(1.01–2.81)
P = 0.03230-day mortality
3.60(2.32–5.35)
P < 0.00011-year mortality
3.10(2.24–4.21)
P < 0.0001Surgical site infection
.94(0.48–1.64)
P = 0.849Acute MI
1.21(0.84–1.69)
P = 0.274Observational data: associations, not effects.
Original publication
Association Between COVID-19 Infection and Postoperative Outcomes Following Coronary Artery Bypass Grafting: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 27 July 2025. doi:10.
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