Perioperative medicine & outcomes
Association between Intraoperative Electroencephalogram Burst Suppression and Postoperative Delirium: A Systematic Review and Meta-analysis
Pooled resultResult — go to the resultPooled odds ratio 1.492 95% CI 1.022–2.178Authors' conclusion
The meta-analysis suggests an association between intraoperative burst suppression and postoperative delirium; however, the quality of evidence was very low.
Study context
- Population
- Adults receiving GA for any surgery (cohort, case-control and randomized studies)
- Participants
- 6,435 adults · 14 studies
- Comparison
- Intraoperative EEG burst suppression vs no burst suppression
- Outcome
- Postoperative delirium (pooled OR, random-effects model)
Methodological detailsrandom-effects model, prospectively registered protocol, PRISMA, Two independent investigators extracted the data
- Random-effects model
- Prospectively registered protocol
- PRISMA
- Two independent investigators extracted the data
Pooled result
As reported in the abstract
Pooled odds ratio
1.492
95% CI 1.022–2.178
Burst suppression vs No burst suppression
pooled OR 1.492 (95% CI 1.022–2.178)
Further pooled results
| Outcome | SMD (95% CI) | |
|---|---|---|
| Intraoperative duration of burst suppression, delirium vs no deliriumI2 = 63%; 95% CI, 16 to 84%; τ2 = 0.027 · significantly longer in patients who developed delirium | 0.462 (0.293–0.632) | |
| Burst suppression ratio, delirium vs no deliriumI2 = 0%; 95% CI, 0 to 85%; τ2 = 0.00 · significantly higher in the delirium group | 0.150 (0.055–0.245) | |
| −0.500.51Difference (linear scale) |
Overall incidence of postoperative delirium
- Overall incidence of postoperative delirium (1,358 of 6,435)
- 21.1%
Original publication
Association between Intraoperative Electroencephalogram Burst Suppression and Postoperative Delirium: A Systematic Review and Meta-analysis. Anesthesiology. Published 10 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →