Perioperative medicine & outcomes
Association between intravenous 5 % albumin administration and acute kidney injury after partial nephrectomy. A retrospective study
Authors' conclusion
Our study suggests that intraoperative administration of 5 % albumin may not be a risk factor for AKI after partial nephrectomy.
Study context
- Population
- Adults undergoing partial nephrectomy729 vs 674 after matching
- Participants
- 1,688 adults
- Exposure
- Intraoperative 5 % albumin vs crystalloids alone
- 5 % albuminn = 809
- Controln = 879reference
- Outcome
- AKI (KIDGO definition)
- Follow-up
- Within 72 h after surgery
Methodological detailssingle-centre, propensity score-based nearest-neighbor matching
- Single-centre
- Propensity score-based nearest-neighbor matching
Main finding
As reported in the abstract
AKI
- 5 % albumin associated with increased risk of acute kidney injury (AKI) (multivariate analysis)
- 32 %
Observational data: associations, not effects.
Original publication
Association between intravenous 5 % albumin administration and acute kidney injury after partial nephrectomy. A retrospective study. J Clin Anesth. Published 14 May 2025. doi:10. 1016/ j. jclinane. 2025. 111873
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