Perioperative medicine & outcomes

Association between intravenous 5 % albumin administration and acute kidney injury after partial nephrectomy. A retrospective study

J Clin AnesthPublished Retrospective cohort study

Authors' conclusion

Our study suggests that intraoperative administration of 5 % albumin may not be a risk factor for AKI after partial nephrectomy.

Study context

Population
Adults undergoing partial nephrectomy729 vs 674 after matching
Participants
1,688 adults
Exposure
Intraoperative 5 % albumin vs crystalloids alone
  • 5 % albuminn = 809
  • Controln = 879reference
Outcome
AKI (KIDGO definition)
Follow-up
Within 72 h after surgery
Methodological detailssingle-centre, propensity score-based nearest-neighbor matching
  • Single-centre
  • Propensity score-based nearest-neighbor matching

Main finding

As reported in the abstract

AKI
5 % albumin associated with increased risk of acute kidney injury (AKI) (multivariate analysis)
32 %

Observational data: associations, not effects.

Original publication

Association between intravenous 5 % albumin administration and acute kidney injury after partial nephrectomy. A retrospective study. J Clin Anesth. Published 14 May 2025. doi:10.1016/j.jclinane.2025.111873

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