ICU sedation, delirium & recovery

Association between multimorbidity and quality of life after hip replacement surgery: analysis of routinely collected patient-reported outcomes

Br J AnaesthPublished Retrospective cohort study

Main finding · Poor QoL outcomes (unchanged/mixed/worse)Result — go to the resultOdds ratio 1.53 95% CI 1.49–1.58

Authors' conclusion

Hip replacement surgery improves QoL. However, patients with multimorbidity are less likely to experience these benefits.

Study context

Population
Patients undergoing total hip replacement in the NHS England Patient Reported Outcome Measures (PROMs) database, April 2013 to March 2018of 216,191 with complete data
Participants
178,129 patients
Exposure
Multimorbidity vs no multimorbidity
  • Multimorbidityn = 38,384
Outcome
Change in QoL (EQ-5D) using the Pareto Classification of Health Change
Follow-up
3 to 6 months postoperative
Methodological detailsroutinely collected patient-reported outcomes, national database (NHS England PROMs), multivariable modelling
  • Routinely collected patient-reported outcomes
  • National database (NHS England PROMs)
  • Multivariable modelling

Main finding

Poor QoL outcomes (unchanged/mixed/worse)

Odds ratio

1.53

95% CI 1.49–1.58

Multimorbidity vs No multimorbidity
OR 1.53 (95% CI 1.49–1.58)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Quality of life (QoL) change after surgery, all patients

Improved
149,774 (84.1%)
Unchanged
10,219 (5.7%)
Worse
7289 (4.1%)
Mixed (≥1 domain improved and ≥1 deteriorated)
10,847 (6.1%)

Number of comorbid diseases

Poor QoL outcomes more frequent as the number of comorbid diseases increased

Original publication

Association between multimorbidity and quality of life after hip replacement surgery: analysis of routinely collected patient-reported outcomes. Br J Anaesth. Published 13 November 2024. doi:10.1016/j.bja.2024.08.037

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