Perioperative medicine & outcomes
Association between pre‐operative prolonged corrected QT interval and all‐cause mortality after non‐cardiac surgery
Authors' conclusion
Pre-operative QTc between 480 and 519 ms is associated with both higher long-term and 30-day mortality after non-cardiac surgery.
Study context
- Population
- Adults over 18 years undergoing non-cardiac surgery at Landspitali-the National University Hospital, Iceland, 2005–2015
- Participants
- 10,209 surgeries
- Exposure
- Pre-operative QTc categories vs reference QTc 380-439 ms
- Outcome
- Long-term mortality
- Follow-up
- Median 2691 days (IQR 1620-3705 days)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Each group vs 380-439Hazard ratio (CI)
≤379
0.85(0.66–1.09)
440-479
1.08(0.99–1.17)
480-519
1.26(1.10–1.43)
≥520
0.97(0.78–1.21)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | OR (CI) | |
|---|---|---|
| 30-day mortality · 30 days≤379 vs 380-439 | 1.12 (0.18–3.8) | |
| 30-day mortality · 30 days440-479 vs 380-439 | 1.03 (0.70–1.51) | |
| 30-day mortality · 30 days480-519 vs 380-439 | 1.64 (1.02–2.60) | |
| 30-day mortality · 30 days≥520 vs 380-439 | 0.98 (0.44–2.06) | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Association between pre‐operative prolonged corrected QT interval and all‐cause mortality after non‐cardiac surgery. Acta Anaesthesiol Scand. Published 21 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →