ICU sedation, delirium & recovery

Association Between Preexisting Mental Health Disorders and Adverse Outcomes in Adult Intensive Care Patients: A Data Linkage Study

Crit Care MedPublished Retrospective cohort study

Authors' conclusion

The presence of a preexisting mental health disorder is associated with greater ICU length of stay and higher rates of invasive ventilation, suggesting these patients may have a different clinical trajectory to patients with no mental health history.

Study context

Population
All patients admitted to eight Australian adult ICUs in 2019 (readmissions within the same hospitalization excluded)58% male
Participants
16,228 patients
Exposure
Preexisting mental health disorder vs none
  • Preexisting mental health disordern = 5,044
Outcome
Prevalence of preexisting mental health disorder
Methodological detailsmulticentre, data linkage, natural language processing
  • Multicentre
  • Data linkage
  • Natural language processing

Main finding

As reported in the abstract

Prevalence of documented preexisting mental health disorder

Preexisting mental health disorder

31.1%

5,044

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)
Invasive ventilationMixed-effects regression1.42 (1.30–1.56)
Outcomeβ-coefficient (95% CI)
ICU LOS13% longer ICU stay · mixed-effects regression0.12 (0.10–0.15)

Affective disorders (most common subtype)

Affective disorders, n (%) of all patients
2,633 (16.2%)

Anxiety disorders

Anxiety disorders, n (%) of all patients
1,611 (9.9%)

Severity of illness and ICU mortality

Similar in both groups

Original publication

Association Between Preexisting Mental Health Disorders and Adverse Outcomes in Adult Intensive Care Patients: A Data Linkage Study. Crit Care Med. Published 8 February 2023. doi:10.1097/ccm.0000000000005792

Composed by AI from the published abstract and checked against it. How Briefs are made →

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