Association between the preoperative N-terminal pro-B-type natriuretic peptide and acute kidney injury in gastrointestinal surgery patients managed with enhanced recovery strategy: a retrospective cohort study
Main finding · Postoperative AKIResult — go to the resultAdjusted odds ratio 1.75 95% CI 1.12–2.73Authors' conclusion
Increased preoperative NT-proBNP is associated with an elevated risk of postoperative AKI in patients who underwent gastrointestinal surgery and managed with ERAS strategy.
Study context
- Population
- Adults (≥18 y) undergoing elective gastrointestinal surgery managed with enhanced recovery after surgery (ERAS) strategy, Xijing Hospital, May 2017–June 20221,932 records screened
- Participants
- 629 adults
- Exposure
- High vs low preoperative NT-proBNP
- Outcome
- Incidence of postoperative AKI
Methodological detailssingle-centre
- Single-centre
Main finding
Postoperative AKI
Adjusted odds ratio
1.75
95% CI 1.12–2.73
By group
High NT-proBNP vs Low NT-proBNP
aOR 1.75 (95% CI 1.12–2.73)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Overall postoperative acute kidney injury (AKI) incidence
- Developed postoperative AKI
- 112 (17.8%)
Original publication
Association between the preoperative N-terminal pro-B-type natriuretic peptide and acute kidney injury in gastrointestinal surgery patients managed with enhanced recovery strategy: a retrospective cohort study. Perioper Med (Lond). Published 22 April 2025. doi:10.
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