Pain medicine

Association Between Prescription Drug Monitoring Program Use Mandate and Opioid Prescribing and Patient-reported Outcomes After Surgery

Ann SurgPublished Interrupted time series analysis

Authors' conclusion

Following the implementation of Michigan's PDMP use mandate, the duration of opioid prescriptions decreased, but patient-reported outcomes did not worsen.

Study context

Population
Adults undergoing general surgical procedures, Michigan, January 2017 to October 2019
Participants
21,897 adults
Exposure
After vs before Michigan's prescription drug monitoring program (PDMP) use mandate
Outcome
Monthly mean days supplied in dispensed opioid prescriptions (filled within 3 days of discharge)
Methodological detailsstatewide surgical registry linked to PDMP database, segmented regression
  • Statewide surgical registry linked to PDMP database
  • Segmented regression

Main finding

As reported in the abstract

Mean days supplied in dispensed opioid prescriptions (level change at mandate)

Mandate associated with level decrease in mean days supplied in dispensed opioid prescriptions

−0.5

95% CI −0.8, −0.2

Observational data: associations, not effects.

Further findings

Patient-reported outcomes (pain in week after surgery, care satisfaction, regret)

Mandate not associated with worsened patient-reported outcomes

Patients with Narx scores ≥200 (subgroup)

Findings similar among patients with Narx scores ≥200

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association Between Prescription Drug Monitoring Program Use Mandate and Opioid Prescribing and Patient-reported Outcomes After Surgery. Ann Surg. Published 8 May 2024. doi:10.1097/sla.0000000000006332

Composed by AI from the published abstract and checked against it. How Briefs are made →

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