The Association of Cannabis Use After Discharge From Surgery With Opioid Consumption and Patient-reported Outcomes
Main finding · Postdischarge opioid consumption (opioid pills)Result — go to the resultAdditional opioid pills 1.0 opioid pills 95% CI 0.4–1.5Authors' conclusion
Patient-reported cannabis use, to treat postoperative pain, was associated with increased opioid consumption after discharge from surgery that was of clinically insignificant amounts, but worse pain and other postoperative patient-reported outcomes.
Study context
- Population
- Patients undergoing 16 procedure types at 69 Michigan Surgical Quality Collaborative hospitals, January–October 2021
- Participants
- 11,314 patients · 69 hospitals
- Exposure
- Cannabis use vs no cannabis use for pain after discharge from surgery
- Cannabisn = 581
- Outcome
- Postdischarge opioid consumption
Methodological detailsmulticentre registry
- Multicentre registry
Main finding
Postdischarge opioid consumption (opioid pills)
Additional opioid pills
1.0 opioid pills
95% CI 0.4–1.5
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) | |
|---|---|---|
| Moderate-to-severe surgical site pain · 1 week | 1.7 (1.4–2.1) | |
| Moderate-to-severe surgical site pain · 1 month | 2.1 (1.7–2.7) | |
| 0.20.5125Adjusted odds ratio (log scale) |
High satisfaction
P < 0.001
Best quality of life
P < 0.001
No regret to undergo surgery
P < 0.001
Original publication
The Association of Cannabis Use After Discharge From Surgery With Opioid Consumption and Patient-reported Outcomes. Ann Surg. Published 28 August 2023. doi:10. 1097/ sla. 0000000000006085
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