Association between sedation during spinal anesthesia and mortality in older patients undergoing hip fracture surgery: A nationwide retrospective cohort study in Japan
Main findingResult — go to the resultHazard ratio 0.92 95% CI 0.59–1.44Authors' conclusion
There was no association between sedation during hip fracture surgery in older patients under spinal anesthesia and postoperative mortality.
Study context
- Population
- Patients aged ≥65 years undergoing hip fracture surgery under spinal anesthesia, acute and subacute care hospitals in Japan, April 2014–May 2022
- Participants
- 25,554 patients · 4,735 matched pairs
- Exposure
- Sedation vs no sedation during spinal anesthesia
- Sedationn = 4,735
- Non-sedationn = 4,735reference
- Outcome
- Postoperative in-hospital all-cause mortality
- Follow-up
- 30 days
Methodological detailspropensity-score matched, nationwide
- Propensity-score matched
- Nationwide
Main finding
As reported in the abstract
Hazard ratio
0.92
95% CI 0.59–1.44
Sedation vs Non-sedation
HR 0.92 (95% CI 0.59–1.44)
Observational data: associations, not effects.
Original publication
Association between sedation during spinal anesthesia and mortality in older patients undergoing hip fracture surgery: A nationwide retrospective cohort study in Japan. J Clin Anesth. Published 11 November 2023. doi:10.
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