Cardiac arrest & resuscitation
The association of mechanical versus manual chest compressions with neurological outcomes at hospital discharge among out-of-hospital cardiac arrests treated with intra-arrest transport
Main findingResult — go to the resultAdjusted odds ratio 0.93 95% CI 0.51–1.69Authors' conclusion
Among cases treated with IAT, we did not detect an association between MCC, compared to manual chest compressions, and favorable neurological outcome at hospital discharge.
Study context
- Population
- Adults with non-traumatic out-of-hospital cardiac arrests (OHCA) transported to hospital with ongoing chest compressions, British Columbia Cardiac Arrest Registry, January 2019 - June 2025treated with intra-arrest transport (IAT)
- Participants
- 1,967 adults
- Exposure
- Mechanical vs manual chest compressions during intra-arrest transport
- Mechanical chest compression (MCC)n = 243
- Manualn = 1,724reference
- Outcome
- Favorable neurological outcome (Cerebral Performance Category 1-2)
- Follow-up
- Hospital discharge
Methodological detailsregistry-based, adjusted logistic regression
- Registry-based
- Adjusted logistic regression
Main finding
As reported in the abstract
Adjusted odds ratio
0.93
95% CI 0.51–1.69
Events by group
MCC vs Manual
aOR 0.93 (95% CI 0.51–1.69)
Observational data: associations, not effects.
Further findings
ROSC at hospital arrival
Survival to hospital discharge
Original publication
The association of mechanical versus manual chest compressions with neurological outcomes at hospital discharge among out-of-hospital cardiac arrests treated with intra-arrest transport. Resuscitation. Published 19 February 2026. doi:10. 1016/ j. resuscitation. 2026. 111020
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