Cardiac arrest & resuscitation

The association of mechanical versus manual chest compressions with neurological outcomes at hospital discharge among out-of-hospital cardiac arrests treated with intra-arrest transport

ResuscitationPublished Retrospective cohort study

Main findingResult — go to the resultAdjusted odds ratio 0.93 95% CI 0.51–1.69

Authors' conclusion

Among cases treated with IAT, we did not detect an association between MCC, compared to manual chest compressions, and favorable neurological outcome at hospital discharge.

Study context

Population
Adults with non-traumatic out-of-hospital cardiac arrests (OHCA) transported to hospital with ongoing chest compressions, British Columbia Cardiac Arrest Registry, January 2019 - June 2025treated with intra-arrest transport (IAT)
Participants
1,967 adults
Exposure
Mechanical vs manual chest compressions during intra-arrest transport
  • Mechanical chest compression (MCC)n = 243
  • Manualn = 1,724reference
Outcome
Favorable neurological outcome (Cerebral Performance Category 1-2)
Follow-up
Hospital discharge
Methodological detailsregistry-based, adjusted logistic regression
  • Registry-based
  • Adjusted logistic regression

Main finding

As reported in the abstract

Adjusted odds ratio

0.93

95% CI 0.51–1.69

Events by group

MCC vs Manual
aOR 0.93 (95% CI 0.51–1.69)

Observational data: associations, not effects.

Further findings

ROSC at hospital arrival

Survival to hospital discharge

Original publication

The association of mechanical versus manual chest compressions with neurological outcomes at hospital discharge among out-of-hospital cardiac arrests treated with intra-arrest transport. Resuscitation. Published 19 February 2026. doi:10.1016/j.resuscitation.2026.111020

Composed by AI from the published abstract and checked against it. How Briefs are made →

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