Association of Age, Sex and American Society of Anaesthesiologists (ASA) Physical Status With Bispectral Index Values During General Anaesthesia: A Large Observational Cohort Study
Authors' conclusion
In this large observational cohort, older patients, patients with higher ASA score and females exhibited lower BIS values during general anaesthesia compared with younger, healthier and male patients, even when anaesthetic dosing followed standard protocols.
Study context
- Population
- Patients who underwent GA between 1 January 2017 and 31 December 202026,650 with continuous BIS
- Participants
- 97,733 patients
- Exposure
- BIS values by age, sex and ASA score
- Outcome
- Associations between BIS values and age, sex and ASA score
Methodological detailslarge-scale, electronic health records
- Large-scale
- Electronic health records
Main finding
As reported in the abstract
BIS values by age, sex and ASA score
- Higher ASA scores, increasing age and female sex associated with deeper anaesthesia with significantly lower BIS values
Observational data: associations, not effects.
Further findings
Use of BIS monitoring
- BIS monitoring more frequent in ASA 1 or 2 and in TIVA
Original publication
Association of Age, Sex and ASA Physical Status With Bispectral Index Values During General Anaesthesia: A Large Observational Cohort Study. Acta Anaesthesiol Scand. Published 14 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →