Perioperative medicine & outcomes

Association of amisulpride and recovery room length of stay among patients with postoperative nausea and vomiting following outpatient surgery

J Clin AnesthPublished Retrospective cohort study

Main finding · PACU LOS (adjusted)Result — go to the resultReduction 26.1 min

Authors' conclusion

This study demonstrated that amisulpride was associated with a significant decrease in PACU length of stay among patients with PONV in a single outpatient surgery center.

Study context

Population
Patients with postoperative nausea and vomiting (PONV) after GA at a single ambulatory surgery center, 2018–2023
Participants
816 patients
Exposure
Amisulpride vs no amisulpride in PACU anti-emetic regimen
Outcome
PACU LOS
Methodological detailssingle-centre, mixed-effects multivariable segmented regression
  • Single-centre
  • Mixed-effects multivariable segmented regression

Main finding

PACU LOS (adjusted)

Reduction

26.1 min

P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

PACU LOS (unmatched univariate analysis) · no significant difference

P = 0.07

Original publication

Association of amisulpride and recovery room length of stay among patients with postoperative nausea and vomiting following outpatient surgery. J Clin Anesth. Published 14 June 2024. doi:10.1016/j.jclinane.2024.111529

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