Association of body mass index with mortality of sepsis or septic shock: an updated meta-analysis
Authors' conclusion
Overweight and obese BMIs (25.0-39.9 kg/m2) are associated with reduced mortality of patients with sepsis or septic shock, although such survival advantage was not found in all crowds.
Study context
- Population
- Sepsis or septic shock patients aged > 18 years
- Participants
- 105,159 participants · 15 studies
- Comparison
- Overweight, obese and morbidly obese body mass index (BMI) vs reference BMI
- Outcome
- Mortality
Methodological detailsfixed-effect or random-effect models, subgroup analyses, Newcastle-Ottawa Scale for quality assessment
- Fixed-effect or random-effect models
- Subgroup analyses
- Newcastle-Ottawa Scale for quality assessment
Pooled result
As reported in the abstract
Odds ratio (95% CI)
Overweight
0.79(0.70–0.88)
Obese
0.74(0.67–0.82)
Morbidly obesity
0.91(0.62–1.32)
Further pooled results
Mortality, patients aged ≤ 50 years (subgroup)
| OR (95% CI) | ||
|---|---|---|
| OverweightAssociation not significant | 0.89 (0.68–1.14) | |
| ObeseAssociation not significant | 0.77 (0.50–1.18) | |
| 0.512Odds ratio (log scale) |
Original publication
Association of body mass index with mortality of sepsis or septic shock: an updated meta-analysis. J Intensive Care. Published 3 July 2023. doi:10.
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